Our technology
Oxygen Imaging
O2M's core technology is inversion recovery pulsed electron paramagnetic resonance oxygen imaging (EPROI) invented by O2M's co-founders.
EPROI is a noninvasive oxygen mapping technology.
It measures the relaxation maps of a water-soluble, oxygen-reporting trityl molecule (OXO63 or its deuterated version OXO71, also known as OXO63-D24) that distributes in a body upon injection. Oxygen concentration is linearly related to trityl relaxation rates.
Tissue oxygen maps obtained using our technology can be used to develop enhanced therapies.
The examples include but are not limited to:
- Cancer research, diagnostics, and treatment
- Assessment of therapy outcome
- Development of artificial cell replacement devices
- Drug development
- Vitality probing of artificial cell replacement devices
Electron Paramagnetic Resonance
- Zeeman effect – splitting of magnetic particle energy levels into several states in the presence of a static magnetic field
- The transition between these states results in absorption or emission of power
- The transition can be excited using oscillating magnetic field with particular frequency – magnetic resonance
How EPROI is Different from MRI
Magnetic Field vs Penetration Depth in EPROI
