Blog
Research highlights and product information
Newsletter
Oxygen Imaging of Cells for Viability Assessment
Cell viability is an essential measurement for cell therapy, tissue-engineered medical products (TEMPs), drug development, and many other biological processes and products. These systems rely on viabl
October 2025
Product Information
LiteAPM: Transportable Lightweight Small Animal Physiological Monitor
We're excited to introduce a Transportable Lightweight Small Animal Physiological Monitor, LiteAPMTM, a compact and portable solution designed to bring peace of mind and precision to your small animal
August 2025
Newsletter
Quantification of Blood-Brain Barrier Leakage and Brain Oxygen Through EPR Imaging
Did you know that BBB leakage can be quantified non-invasively with EPR Imaging? In a healthy brain, the EPR imaging contrast agent, trityl OXO71, is blocked by the blood-brain barrier (BBB), but gues
July 2025
Newsletter
Accelerated EPR Imaging using Deep Learning Denoising
As OXO71-based Electron Paramagnetic Resonance Oxygen Imaging (EPROI) transitions from small to large animal models, and ultimately to humans, various challenges must be addressed. Long acquisition ti
April 2025
Newsletter
Mouse Abdominal pO2 Imaging and Assessment of Subcutaneously Implanted Cell Therapy Devices
Type 1 diabetes (T1D) is an autoimmune disease that leads to the loss of insulin-producing pancreatic beta cells. Beta cell replacement devices or bioartificial pancreas (BAP) have shown promise in cu
January 2025
Newsletter
Oxygen Imaging and Tumor Radiotherapy
Cancer is a major public health problem worldwide and is the second leading cause of death in the United States. About two-thirds of cancer patients are treated with radiation, either alone or in comb
January 2023
Newsletter
Oxygen Sensitive Trityl Radical OXO71
Magnetic resonance imaging (MRI) and electron paramagnetic resonance oxygen imaging (eMRI or EPROI) are fundamentally based upon the same principles, however a key difference is the resonant species.
August 2022
Newsletter
Finding the Best Site for Tissue Graft Implantation
Oxygen sensitive LiPc probes implanted within the right dorsum subcutaneously, reporting oxygen tension over 6 weeks. Data obtained by JIVA-25™ oxygen imager. Tissue engineered grafts and cell encapsu
June 2022
Newsletter
Biomaterial Assessment Using Oxygen Imaging
Biomaterials that host live cells must overcome the crucial hurdle of sustaining sufficient oxygenation for cell survival. Several approaches for improving oxygenation within the biomaterials have bee
April 2022
Newsletter
Accelerating Towards a Cure for Type 1 Diabetes
Type 1 diabetes mellitus (T1D) is an autoimmune disease causing insufficient or no production of insulin from the pancreas; this impedes glucose metabolism, generating several life-long health sequela
December 2021
Newsletter
O2M is at RSNA 2021!
Come meet Team O2M at RSNA 2021! Our Demo JIVA-25 allows you to capture oxygen images of a "mouse." We are located in the New Vendors Exhibition Hall, booth #2402.
November 2021
Newsletter
A Lesson From Insects on Overcoming Cell Encapsulation Hypoxia
Inadequate oxygenation is a major challenge in cell encapsulation, a therapy which holds potential to treat many diseases including type I diabetes. In such systems, cellular oxygen (O2) delivery is l
November 2021
Newsletter
Tumor Hypoxia Imaging
Axial slices of SCC7 squamous cell carcinoma in mouse leg of MRI, PO2 by JIVA-25™, and CT. Tumor contoured in pink. Photo credit: Howard Halpern Lab, The University of Chicago Tissue oxygenation is de
October 2021
Product Information
O2M Will Build the World’s First Clinical Oxygen Imager
The 2019 Nobel Prize in medicine for the discovery of oxygen signaling pathways highlights the importance of oxygenation as a physiologic parameter. Oxygenation, the delivery of oxygen to cells and ti
October 2021
Product Information
O2M's Oxygen Measurement Core
O2M's "Oxygen Measurement Core" is a contract research facility. It provides full cycle in vitro and small animal in vivo oxygen measurement services. All experiments are performed using O2M's preclin
July 2021
Newsletter
The First Publication from "Oxygen Measurement Core"
Cell encapsulation represents a promising therapeutic strategy for many hormone-deficient diseases such as type I diabetes (T1D). However, adequate oxygenation of the encapsulated cells remains a chal
June 2021
Newsletter
In Vivo Oxygen Imaging of Islet Encapsulation Devices using JIVA-25™
Did you know that JIVA-25™ can provide in vivo partial oxygen pressure (pO2) maps of an implanted devices in a rodent? The pO2 maps provide a crucial missing information to assess the success of all t
May 2021
Newsletter
O2M at the "Society for Biomaterials 2021 Annual Meeting"
Rapid Fire Presentations 558: In Vitro pO2 Measurement of Islet Encapsulation Devices in Oxygen Measurement Core (In collaboration with the University of Chicago, University of Arizona, Cornell Univer
April 2021
Newsletter
Application of Oxygen Imaging to Oxygen Microbubble Therapy
Hypoxia severely limits the efficacy of radiotherapy, chemotherapy, and immunotherapy. This results in diminished success in treating cancer. Despite consistent research in this field and treatments w
December 2020
Newsletter
Oxygen Guided Radiation Therapy
Spatial heterogeneity in tumor hypoxia is one of the most important factors regulating tumor growth, development, aggressiveness, metastasis, and effective treatment outcome. Most solid tumors are cha
November 2020