About Us
About O2M Technologies
O2M Technologies, LLC is a Chicago-based startup specializing in electron paramagnetic resonance (EPR) oxygen imaging, building on the pulse EPR oxygen imaging (EPROI) technique. Co-founded by Dr. Mrignayani Kotecha (CEO), Dr. Boris Epel (CTO) and Dr. Howard J. Halpern in 2017, the company offers oxygen imaging instruments and services for regenerative medicine and pre-clinical cancer studies, with its trityl-based technology and flagship preclinical instrument, the JIVA-25, providing non-invasive three-dimensional partial oxygen pressure (pO2) maps in tissues. Captured in its motto, “Oxygen Imaging for Efficient Therapies,” O2M’s mission centers on making oxygen — a critical but under-monitored physiological parameter that drives cell growth, differentiation, and death — directly measurable in tissues. By turning pO2 into a quality-control tool for tissue grafts, cell-therapy devices, and artificial organs, and by extending the same technology to preclinical cancer and neurological research, the company aims to improve therapeutic outcomes across regenerative and translational medicine.
Leadership
Mrignayani Kotecha, PhD
President & CEO
Founding member, leads business strategy and innovation in EPR imaging. PhD in Physics. Lead editor of the 2017 Wiley book on MRI in Tissue Engineering. Recipient of the 2024 C. William Hall Award.
Boris Epel, PhD
Chief Technology Officer
Inventor of the core oxygen imaging technology and founding member with 25+ years in EPR imaging hardware and software. Developer of SpecMan4EPR; Research Professor at the University of Chicago. Published the first proof of oxygen-guided radiation therapy.
Howard J. Halpern, MD, PhD
Board Member
Inventor of the core oxygen imaging technology and founding member. Pioneer of EPR oximetry with 35+ years in the field; Professor at the University of Chicago and practicing oncologist.